Neauvia Organic Stimulate (1x1ml)

NEAUVIA ORGANIC STIMULATE

Currently, the most popular source of HA are laboratory strains of Streptococcus. In fact, extracting the precious acid out of them requires the bacteria membrane breaking and application of chemical solvents. Contaminants present in the finished product are precisely the residues of bacteria and solvents. Despite several purifying processes, today’s technology is unable to fully eliminate these impurities. The purest form of hyaluronic acid currently available is obtained from Bacillus subtilis. This bacterium, which is non-pathogenic to humans, produces HA in a process based on water usage.

Protective action of PEG is able to mask the implant from the host organism reducing the risk of immunological reaction and formation of the foreign body giant cells (FBGC). In other words, PEG reduces inflammation and granulomas formation. Moreover, it delays the degradation and the bioabsorbtion of the implant. PEG makes Neauvia fillers the first, one and only BIOMIMETIC fillers worldwide. PEG makes Neauvia Organic the most biocompatible fillers on the market reducing almost to zero the biopotential rejection of the hosting tissues.

IPN stands for Interpenetrating Polymer Network, which is an innovative and advanced technology to combine two different polymers - here HA and PEG - in one network that gives outstanding mechanical, rheological and thermosensitive properties to Neauvia fillers. The use of this technology in Neauvia Organic fillers is possible thanks to PEG, which, unlike other current cross-linker agents, is a polymer.

Thanks to PEG features and to a precise technique of determining the molecular weight of the HA, Neauvia fillers have the most optimal rheology - the ratio of three properties – on the market:

• Cohesivity: the attractive force acting between the molecules of a substance.
• Viscoelasticity: the ratio between Viscosity (the property of resistance to flow in a fluid/semifluid; adjacent layers move parallel to each other with different speeds) and Elasticity (the tendency of solid materials to return to their original shape after being deformed).
• Plasticity: the property to undergo permanent deformation under load.

Neauvia Organic Stimulate is a unique product, the only one which offers not only great filling effect but also a long term biostimulation. The 26 mg/ml of HA is complemented with 1% of calcium hydroxyapatite - a mineral occurring naturally in human body able to stimulate collagen production. Stimulate is a perfect choice every time when a patient is suffering from the lack of volume and density. The product immediately will fill the tissue deficits giving the desired shape and volume gradually improving the quality of the skin. The neocollagenesis process permits a longer lasting correction. Stimulate is made from hyaluronic acid derived from Bacillus subtilis and it is cross-linked by PEG polymer using a real IPN technology. Calcium hydroxyapatite used in Neauvia fillers has small particle size (8-12 microns) and is well spreaded in the cluster of the hydrogel. This assure stability of the particles that have no possibility to migrate..

Benefits:

• Unique combination of filling and biostimulation,
• Significant improvement in skin density level,
• Clinically proved results,
• Ultra-safe profile thanks to Bacillus subtilis and PEG,
• Slow biodegradation and long lasting results.

INDICATIONS

For moderate and strongly aged skin

• deep filling of skin depression (included deep wrinkles and nasolabial folds),
• biostimulation and revitalisation,
• acne scars reduction,
• face contours lifting,
• chin modeling,
• cheek modeling.

COMPOSITION

Hyaluronic Acid, cross-linked: 26 mg/ml

1% CaHA

Glycine and L-Proline

Lidocaine: -

PACKAGE

1 x 1ml prefilled syringe

1 x cannula: 22G 50mm

1 x needle: 21G 16mm

CONTRAINDICATED

• hypersensitivity to one of the components,
• skin infection near the site of injection,
• patients susceptible to keloid formation,
• pregnant or lactating women,
• allergy or anaphylaxis,
• bleeding disorders,
• autoimmune disorders,
• antibiotic therapy.

Read the package leaflet before use.