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Currently, the most popular source of HA are laboratory strains of Streptococcus. In fact, extracting the precious acid out of them requires the bacteria membrane breaking and application of chemical solvents. Contaminants present in the finished product are precisely the residues of bacteria and solvents. Despite several purifying processes, today’s technology is unable to fully eliminate these impurities. The purest form of hyaluronic acid currently available is obtained from Bacillus subtilis. This bacterium, which is non-pathogenic to humans, produces HA in a process based on water usage.
Protective action of PEG is able to mask the implant from the host organism reducing the risk of immunological reaction and formation of the foreign body giant cells (FBGC). In other words, PEG reduces inflammation and granulomas formation. Moreover, it delays the degradation and the bioabsorbtion of the implant. PEG makes Neauvia fillers the first, one and only BIOMIMETIC fillers worldwide. PEG makes Neauvia Organic the most biocompatible fillers on the market reducing almost to zero the biopotential rejection of the hosting tissues.
IPN stands for Interpenetrating Polymer Network, which is an innovative and advanced technology to combine two different polymers - here HA and PEG - in one network that gives outstanding mechanical, rheological and thermosensitive properties to Neauvia fillers. The use of this technology in Neauvia Organic fillers is possible thanks to PEG, which, unlike other current cross-linker agents, is a polymer.
Thanks to PEG features and to a precise technique of determining the molecular weight of the HA, Neauvia fillers have the most optimal rheology - the ratio of three properties – on the market:
Neauvia Organic Stimulate is a unique product, the only one which offers not only great filling effect but also a long term biostimulation. The 26 mg/ml of HA is complemented with 1% of calcium hydroxyapatite - a mineral occurring naturally in human body able to stimulate collagen production. Stimulate is a perfect choice every time when a patient is suffering from the lack of volume and density. The product immediately will fill the tissue deficits giving the desired shape and volume gradually improving the quality of the skin. The neocollagenesis process permits a longer lasting correction. Stimulate is made from hyaluronic acid derived from Bacillus subtilis and it is cross-linked by PEG polymer using a real IPN technology. Calcium hydroxyapatite used in Neauvia fillers has small particle size (8-12 microns) and is well spreaded in the cluster of the hydrogel. This assure stability of the particles that have no possibility to migrate..
For moderate and strongly aged skin
Hyaluronic Acid, cross-linked: 26 mg/ml
Glycine and L-Proline
1 x 1ml prefilled syringe
1 x cannula: 22G 50mm
1 x needle: 21G 16mm
Read the package leaflet before use.