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Galderma Restylane Defyne Lidocaine (1x1ml)
  • Galderma Restylane Defyne Lidocaine (1x1ml)
  • Galderma Restylane Defyne Lidocaine (1x1ml)

Restylane Defyne Lidocaine (1x1ml)


Medical device. Contains lidocaine.

Reduction of deep wrinkles and folds | Lifting of the corners of the mouth | Cheek modeling

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Galderma Restylane Lyft Kysse Refyne Defyne Volyme Lidocaine


Restylane products (formerly Emervel) have been developed using innovative production technology called Optimal Balance Technology, ensuring the optimal consistency of filler gel. As a result, they have good tolerance and long-lasting aesthetic results.

Restylane® Defyne (Emervel® Deep) is a non-animal sourced cross-linked hyaluronic acid, single-phase, transparent, and biodegradable.

Restylane® Defyne is suitable for correcting deep wrinkles such as nasolabial folds and marionette lines, which can cause a tired facial expression. Slight lifting of the corners of the mouth and subtle filling of the folds give the face a more relaxed and friendly appearance. Restylane® Defyne is also suitable for restoring the proper shape of the face in its central part, including periorbital wrinkles, tear troughs, and cheek modeling. Restylane® Defyne contains lidocaine, which helps reduce pain during and after the procedure.

The effects of the treatment last 6 - 9 months, depending on the type and condition of the patient's skin.


The product is injected into deep skin areas or the upper subcutaneous layer for:

  • deep wrinkles and folds,
  • nasolabial folds,
  • marionette lines,
  • reduction of eye wrinkles, e.g.,
  • cheek modeling.


Concentration of cross-linked hyaluronic acid HA: 20 mg/ml

Lidocaine: 0.3%

Physiological buffer at pH 7, quantity adjusted to 1 mL.


1 ampoule-syringe with 1 ml of preparation

2 needles 27G 1/2


  • In areas or surrounding areas where there are inflammatory conditions or skin infections (acne, rash),
  • In combination with peelings, laser therapy, and dermabrasion,
  • Tendency to form hypertrophic scars,
  • Hypersensitivity to hyaluronic acid, mannitol, lidocaine hydrochloride, or locally applied anesthetics,
  • Patients with porphyria,
  • Reduced blood clotting,
  • Allergy, including to chromium and nickel,
  • Taking blood-thinning medications (e.g., Aspirin, Polocard),
  • Pregnant women, breastfeeding mothers, and children,
  • Menstruation,
  • Taking antibiotics (up to 2 weeks after completing antibiotic therapy).


The treatment should be carried out by a specialist familiar with the administration method.

The recommended depth of injection depends on the type of wrinkles and the chosen technique.

Patients should be informed about possible side effects and risks before the treatment. It is recommended to use a prior anesthetic before applying the solution.

After treatment, slight swelling, redness, or minor bruises may occur, which disappear after a few hours to a few days.


Store at a temperature of 0-25°C. Protect from sunlight and frost. Do not freeze. Keep out of the reach of children.



Product for use by professionals only. By purchasing, you declare that you are a doctor or cosmetologist trained in aesthetic medicine.

Before using, please familiarize yourself with the leaflet included in the package.

Specific References



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