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Non-animal cross-linked hyaluronic acid. The main component of Restylane® (before: Emervel®) is hyaluronic acid. This is a naturally occurring substance found in all living organisms. The hyaluronic acid is mixed with a cross-linker called Butanediol Diglycidyl Ether (BDDE) to form a gel, which is then purified through dialysis to remove trace amounts of BDDE left over from the process.
The hyaluronic acid in Restylane® is produced by a biotechnological process from bacterial fermentation without using any animal products.
Restylane® benefits from what the manufacturers call its Optimal Balance Technology™.
Restylane® has 4 levels of cross-linking, resulting in 4 levels of gel firmness across the range. Particle size or calibration is achieved during the manufacturing process after cross-linking, by sieving the gels through different sizes of mesh.
Hyaluronic acid is completely broken down within the skin over a period of months, eventually leaving no trace of the filler.
Restylane®Defyne (Emervel®Deep) has a high volume lifting effect and integrates with the skin matrix to smooth away deep wrinkles or folds such as naso-labial and marionette lines (mouth-to-chin lines). The addition of 0.3% lidocaine ensures comfort during treatment. It is injected into the deep dermis or upper subcutaneous layer.
The Optimal Balance Technology™, employed in the manufacture of Restylane®, provides a product which lasts for 6 - 9 months. In clinical trials, some effects have also been seen at 12 months.
Hyaluronic Acid: 20 mg/ml
1 x 1 ml prefilled syringe
needles: 2 x 27G 1/2 "ultra thin wall"
Read the package leaflet before use.